27 June 2005 00:01 [Source: ICB Americas]
Pfizer has brought on-stream a new facility in Loughbeg, Ireland, dedicated to the production of torcetrapib, a compound being studied in combination with the cholesterol-lowering drug Lipitor (atorvastatin).
The company invested $90 million to expand the Loughbeg facility, which will employ 40 people once fully operational. The plant will use spray-dried dispersion, a new dosage form technology developed in conjunction with Bend Research, to formulate the torcetrapib/atorvastatin combination used in the clinical development program.
The combination drug represents a new strategy in the treatment of cardiovascular diseases: while traditional statins like Lipitor act to lower LDL, or “bad” cholesterol, torcetrapib works to raise levels of HDL, or “good” cholesterol.
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