Isopropanol (IPA) Production and Manufacturing Process

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Two commercial routes to IPA are used. The older method is based on the indirect hydration of refinery-grade propylene using sulphuric acid to form isopropyl sulphate which is then hydrolysed with steam to form sulphuric acid and IPA. The crude IPA is distilled to the desired purity.

 

A more modern route is the direct hydration of chemical grade (90-99%) propylene avoiding the need for sulphuric acid. Propylene and water are heated and the liquid-vapour mixture under pressure passes into a trickle flow reactor containing sulphonated polystyrene cation ion exchange resins. Alternatively, the reaction can be carried out in the gas phase over a phosphoric acid-based fixed bed catalyst. There is also a liquid phase route employing a soluble tungsten catalyst. The IPA is obtained from the aqueous solution by distillation.

 

A very small amount of IPA is produced by the hydrogenation of acetone in the liquid phase. This process is only suitable where excess acetone is available.

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Isopropanol Uses and Outlook

The main use for isopropanol (IPA) is in solvents with outlets in cosmetics and personal care products, de-icers, paints and resins, pharmaceuticals, food, inks and adhesives. It is also used as solvent for oil and gums and in the manufacture of fishmeal concentrates. Low-grade IPA is used in motor oils. Little or no growth is expected in solvent applications due to stricter regulations on volatile organic compounds (VOCs).
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