Two life cycle opportunities for greening drugs – Newreka

19 February 2010 01:29  [Source: ICIS news]

SAN FRANCISCO (ICIS news)--There are two stages in the life cycle of pharmaceuticals where green chemistry can be most profitably implemented, according to a leader in the field.

Speaking Thursday at the InformexUSA exhibition in San Francisco, Nitesh Mehta, founder and director of India-based Newreka Green-Synth Technologies, noted that high-volume products, particularly generics, present good opportunities for green chemistry to dramatically reduce both environmental impact and manufacturing costs.

Drugs in Phase II and III clinical development present another opportunity, he said. The synthesis is not yet fixed by regulatory submissions, while the products themselves have a good chance of reaching market, he explained.

In either case, he added, the best place to start would probably be the synthetic step with the highest E-factor – that is, the step that produces the greatest waste per unit of product.

“You could do it in house, in collaboration with academic or research institutions, you could hire a professional company that is good at green chemistry, or you could do a combination of all,” he said.

Mehta suggested companies might begin by forming a group within the business focused specifically on promoting green chemistry. Such a group would combine environmentalism with entrepreneurship, a role he called “enviropreneurship”.

“If that kind of concept could be promoted, I think it would accelerate a lot the implementation of green chemistry,” he said.

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By: Clay Boswell
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